2. Signaling Pathways
  3. GPCR/G Protein
  4. Adenosine Receptor
  5. Adenosine A2A receptor (A2AR) Isoform
  6. Adenosine A2A receptor (A2AR) Agonist

Adenosine A2A receptor (A2AR) Agonist

Adenosine A2A receptor (A2AR) Agonists (8):

Cat. No. Product Name Effect Purity
  • HY-N0092
    Inosine
    		Agonist 99.61%
    Inosine is an endogenous purine nucleoside produced by catabolism of adenosine. Inosine has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects. Inosine is an agonist for adenosine A1 (A1R) and A2A (A2AR) receptors.
  • HY-105017
    Evodenoson
    		Agonist 99.74%
    Evodenoson is a selective agonist of the A2A adenosine receptor. Evodenoson’s primary actions include reducing inflammatory responses, decreasing intestinal fluid secretion, edema, tissue damage, and neutrophil infiltration induced by Clostridium difficile toxin A. Evodenoson’s protective effect is achieved by reducing myeloperoxidase (MPO) and adenosine deaminase (ADA) activities, and by lowering the production of tumor necrosis factor-alpha (TNF-α).
  • HY-122231
    MRS3558
    		Agonist
    MRS3558 is a potent and selective A3AR agonist, with Ki values of 0.6 nM for humans and 0.9 nM for rats, making it suitable for research in the fields of neuropathic pain and anesthesia.
  • HY-W777125
    2-Chloro-3-deazaadenosine
    		Agonist
    2-Chloro-3-deazaadenosine is agonists for adenosine receptor, with Kis of 0.3, 0.08, 25.5 and 1.9 μM, for A1, A2A, A2B, and A3 receptors, respectively.
  • HY-103170
    LUF5834
    		Agonist
    LUF5834 is a selective A2B adenosine receptor (A2BR) partial agonist (EC50 = 12 nM). LUF5834 is also a partial A1/A2A adenosine receptor agonist (lacking selectivity) with Ki values of 2.6 and 28 nM, respectively.
  • HY-14851
    MRE 0094
    		Agonist
    MRE 0094 (Sonedenoson) is a selective activator for adenosine receptor A2A, with a Ki of 490 nM. MRE 0094 exhibits anti-platelet and anti-inflammatory activities.
  • HY-108193
    GW 328267
    		Agonist
    GW 328267 is an A2A receptor agonist. GW 328267 can be used for research of asthma, COPD and upper respiratory inflammatory disease.
  • HY-137370
    2-Hexynyl-5′-N-ethylcarboxamidoadenosine
    		Agonist
    2-Hexynyl-5′-N-ethylcarboxamidoadenosine (HENECA) is a selective A2A adenosine receptor agonist. 2-Hexynyl-5′-N-ethylcarboxamidoadenosine increases intracellular cAMP level, and inhibits TNFα-evoked MMP-3 release. 2-Hexynyl-5′-N-ethylcarboxamidoadenosine induces Aβ42 production in SH-SY5Y cells.